کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3149298 | 1197448 | 2006 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Immunoelectron Microscopic Analysis of CD11c-Positive Dendritic Cells in the Periapical Region of the Periodontal Ligament of Rat Molars
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
دندانپزشکی، جراحی دهان و پزشکی
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![عکس صفحه اول مقاله: Immunoelectron Microscopic Analysis of CD11c-Positive Dendritic Cells in the Periapical Region of the Periodontal Ligament of Rat Molars Immunoelectron Microscopic Analysis of CD11c-Positive Dendritic Cells in the Periapical Region of the Periodontal Ligament of Rat Molars](/preview/png/3149298.png)
چکیده انگلیسی
To increase understanding of structural and phenotypic characteristics of dendritic cells (DCs) in the periapical region of the periodontal ligament (PDL) of rat molars, we performed immunoelectron microscopy for CD11c, a previously untested DC marker. Results demonstrated that CD11c clearly recognized DCs, although it also labeled certain macrophage subpopulation(s). In the normal PDL, resident DCs that extended several long cytoplasmic processes from their oval to slender cell body were identified. When the PDL was bacterially challenged by three days of unsealed pulp exposure, relatively small, irregularly shaped DCs with many thin and short cytoplasmic processes, most likely representing newly recruited DCs, were detected. The ratio of DCs in CD11c+ cells was significantly higher than that in ED1 (anti-macrophages and DCs)-positive and OX6 (anti-major histocompatibility complex class II molecules)-positive cells in normal and challenged PDL.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Endodontics - Volume 32, Issue 12, December 2006, Pages 1164-1167
Journal: Journal of Endodontics - Volume 32, Issue 12, December 2006, Pages 1164-1167
نویسندگان
Liying DDS, MS, Tomoatsu DDS, PhD, Takashi DDS, PhD, Minoru DDS, PhD, Hideaki DDS, PhD,