In Vitro Evaluation of the Sealing Ability of Newly Developed Calcium Phosphate–based Root Canal Sealer

This study compared the sealing ability of newly developed calcium phosphate–based root canal sealers (CAPSEAL I, CAPSEAL II) with other calcium phosphate–based sealer (Sankin Apatite Root Canal Sealer: SARCS I, SARCS III), a resin-based sealer (AH Plus), a ZOE-based sealer (Pulp Canal Sealer EWT), and a calcium hydroxide–based sealer (Sealapex) by using an anaerobic bacterial leakage model with Prevotella nigrescens during a 90-day observation period (n = 15/group). SARCS I and III had significantly greater leakage with P. nigrescens than all other groups (P < .05). There was no other statistical difference between the sealers. Field emission–scanning electron microscope observations showed that both CAPSEAL I and II sealers were well-adapted to the canal wall and infiltrated into the dentinal tubules.