Effect of Preoperative Ibuprofen on the Success of the Inferior Alveolar Nerve Block in Patients with Irreversible Pulpitis

The success rate for the IAN block was 41% with ibuprofen and 35% with placebo, with no significant difference (P = .57) between the 2 groups. For mandibular posterior teeth, a dose of 800 mg of ibuprofen given 45 minutes before the administration of the IAN block did not result in a statistically significant increase in anesthetic success in patients with irreversible pulpitis.