Comparative evaluation of efficacy of tissue glue and sutures after surgical removal of impacted mandibular third molars – A prospective controlled clinical study

ObjectiveTo evaluate the efficacy, advantages, and disadvantages of cyanoacrylate glue (Iso Amyl 2-Cyanoacrylate) for sutureless wound closure after surgical removal of impacted mandibular third molars.Materials and methodsFifty patients with bilaterally symmetrical impacted mandibular third molars were studied in this controlled clinical trial. On the control side closure after surgical removal of third molar was done with conventional sutures and with cyanoacrylate glue on the study side.ResultsThe data analysis showed that the severity of postoperative pain with cyanoacrylate glue method was less significant than with suturing on the 1st, 2nd, and 7th day after surgery whereas postoperative bleeding and swelling with cyanoacrylate glue method were less significant than with suturing on the 1st postoperative day.ConclusionThis study suggested that the efficacy of both, cyanoacrylate glue and suturing, was similar in wound healing, but the use of cyanoacrylate glue showed better hemostasis, decreased pain and swelling and was expeditious.