کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3160974 1198592 2015 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Emergence of multidrug resistant enterococci at a tertiary care centre
ترجمه فارسی عنوان
ظهور انتروکوک مقاوم در برابر داروهای چندگانه در مرکز مراقبت های ویژه
کلمات کلیدی
انتروکوک مقاوم در برابر چندین دارو؛ آزمایش حساسیت ضد میکروبی؛ حداقل غلظت مهارکننده؛ مقاومت سفالوسپورین در سطح بالا. مقاومت گلیکوپپتیدها
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی دندانپزشکی، جراحی دهان و پزشکی
چکیده انگلیسی

BackgroundEnterococci have assumed great clinical importance because of their increasing resistance to various antimicrobial agents. Thus, knowledge about the antibiogram of these multidrug resistant isolates is of utmost importance in formulating an effective antibiotic policy to treat these infections and reducing the morbidity and mortality. Aim of this study was to assess the antimicrobial resistance pattern of enterococci and determine the prevalence of multidrug resistance among them.MethodsThis cross sectional study was carried out from August 2011 to February 2014, in which 200 non-repetitive clinical isolates of enterococci were included. Antimicrobial susceptibility testing was done by disc diffusion method. Minimum inhibitory concentration (MIC) of gentamicin, streptomycin, vancomycin, teicoplanin and linezolid was determined by E-test method.ResultsThe prevalence of multidrug resistance among enterococcal isolates was found to be 63%. Varying levels of resistance was seen to various antibiotics. Most of the isolates were resistant to penicillin (95%), ampicillin (95%) and cotrimoxazole (90%). High level aminoglycoside resistance (HLAR) and glycopeptide resistance was seen in 39% and 14% isolates respectively. Only 4 isolates (2%) were found to be resistant to linezolid.ConclusionThe prevalence of multidrug resistance among enterococci was found to be 63%, the resistance being more common in Enterococcus faecium as compared to Enterococcus faecalis. The study highlights the emergence and increased prevalence of multidrug resistant enterococci which pose a serious therapeutic challenge.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Medical Journal Armed Forces India - Volume 71, Issue 2, April 2015, Pages 139–144
نویسندگان
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