Transforming growth factor-β1 activates ΔNp63/c-Myc to promote oral squamous cell carcinoma

OSCC proliferation is manifested by the induction of c-Myc in response to TGF-β1 signaling, which is essential for OSCC growth. Our data highlight the potential role of TGF-β1 in the induction of cancer progression and invasion of OSCC.