کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3166365 1199112 2016 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Prospectively-collected, tooth-specific dosimetry correlated with adverse dental outcomes
ترجمه فارسی عنوان
دزیمتری اختصاصی با دقت مورد نظر جمع آوری شده و با پیامدهای نامطلوب دندانی مرتبط است
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی دندانپزشکی، جراحی دهان و پزشکی
چکیده انگلیسی

ObjectivesTo correlate radiation dose to specific tooth-bearing portions of bone with adverse dental outcomes.Study DesignEighty-nine patients treated with intensity-modulated radiation therapy with or without chemotherapy had radiation dose to specific tooth-bearing portions of the mandible and the maxilla. Data were collected prospectively during treatment planning, which resulted in 2490 data points. These patients underwent a comprehensive dental intake evaluation that included measurement of pocket depths and were then followed up with serial dental evaluations for a median of 2.5 years (range 0.2–6.9 years).ResultsAt the patient level, the 3-year risks of osteoradionecrosis (ORN) and periodontal disease were 2.5% and 36.6%, respectively. For any individual tooth, the risks of ORN and periodontal disease were 0.1% and 5.1%, respectively, at 3 years. Radiation dose to individual tooth–bearing portions of bone was correlated with ORN development (P = .0165). Periodontal disease also demonstrated a significant, but more gradual, dose response (P = .0395).ConclusionsAdverse dental outcomes directly correlate with increased tooth-specific doses.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology - Volume 122, Issue 2, August 2016, Pages 158–163
نویسندگان
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