کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3194582 | 1201399 | 2012 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Structure and function of the epidermis related to barrier properties
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موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
امراض پوستی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Structure and function of the epidermis related to barrier properties Structure and function of the epidermis related to barrier properties](/preview/png/3194582.png)
چکیده انگلیسی
The most important function of the skin is the formation of a barrier between the “inside” and the “outside” of the organism, which prevents invasion of pathogens and fends off chemical assaults as well as the unregulated loss of water and solutes. The physical barrier is mainly localized in the stratum corneum, which consists of protein-enriched cells and lipid-enriched intercellular domains. Any modifications in epidermal differentiation and lipid composition results in altered barrier function, a central event in various skin alterations and diseases. This contribution presents a brief description of the structure of the skin, paying attention to the most important components responsible for skin barrier function.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Clinics in Dermatology - Volume 30, Issue 3, May–June 2012, Pages 257–262
Journal: Clinics in Dermatology - Volume 30, Issue 3, May–June 2012, Pages 257–262
نویسندگان
Adone Baroni, Elisabetta Buommino, Vincenza De Gregorio, Eleonora Ruocco, Vincenzo Ruocco, Ronni Wolf,