Muir-Torre syndrome: Facts and controversies

The cutaneous presentation of a tumor sometimes has implications for a patient and his or her family, and Muir-Torre syndrome is an example of this. Because a single skin lesion can have broad consequences, it is important for clinicians to be aware of Muir-Torre syndrome. The definition, potential clues, the role of ancillary testing (microsatellite, immunohistochemical, and genetic), and screening recommendations are reviewed.