کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3226139 1588154 2010 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Early risk stratification with simple clinical parameters for cirrhotic patients with acute upper gastrointestinal bleeding
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی طب اورژانس
پیش نمایش صفحه اول مقاله
Early risk stratification with simple clinical parameters for cirrhotic patients with acute upper gastrointestinal bleeding
چکیده انگلیسی

ObjectiveThis study aimed to identify pre-endoscopic clinical parameters independently associated with 6-week mortality and to develop a prognostic model in cirrhotic patients with acute upper gastrointestinal (UGI) bleeding.MethodsA total of 542 consecutive admissions of 389 cirrhotic patients with acute UGI bleeding were retrospectively investigated. Pertinent clinical data obtained at the emergency department were analyzed. Multivariate logistic regression analysis was performed to determine risk factors for 6-week mortality and to develop a predictive model.ResultsForty-four patients (8.12%) died within 6 weeks. The 6-week mortality was independently associated with male sex, hepatocellular carcinoma, non–hepatocellular carcinoma malignancy, hypoxemia with peripheral oxygen saturation less than 95%, serum bilirubin, and prothrombin time. A predictive model consisting of these 6 simple parameters was built. The c statistic of our model was 0.84, significantly superior to that (0.71) of the model for end-stage liver disease score (P = .002).ConclusionsSimple pre-endoscopic clinical parameters are valuable for early risk stratification in cirrhotic patients with acute UGI bleeding. Our prognostic model warrants prospective validation by further studies.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: The American Journal of Emergency Medicine - Volume 28, Issue 8, October 2010, Pages 884–890
نویسندگان
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