The study of congenital cytomegalovirus, Rubella and Herpes Simplex Virus-2 infections in infants

AimsThe study was conducted to analyze the role of Cytomegalovirus (CMV), Rubella and Herpes Simplex Virus (HSV-2) as an etiological agent in congenital infections in infants.Material and methodsThe study was carried out at National Reference Centre i.e. NCDC, Delhi where samples are referred from various government hospitals of Delhi from the period of January 2013–December 2013. The samples were tested for CMV, Rubella and HSV specific IgM antibodies by μ capture ELISA (Enzyme linked Immunoassay).ResultsIn children the overall positivity of CMV, Rubella and HSV-specific IgM antibodies was 20.7%, 5.4%, and 2.3% respectively.ConclusionThe study indicated that maternal infection with CMV, Rubella and HSV-2 is a major contributory factor for congenital infections in neonates and infants and therefore screening for these viruses in early pregnancy should be made mandatory.