کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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3235192 | 1205442 | 2008 | 4 صفحه PDF | دانلود رایگان |

BackgroundOrthotopic liver transplantation (OLT) is the replacement of a diseased liver with a healthy liver in the normal anatomic position. In this study we sought to determine the factors influencing red blood cell (RBC) transfusions during liver transplants. Liver being a highly vascular organ, surgeries like liver transplant may involve massive blood loss making the blood banks a vital factor in the clinical transplantation program.Aims & objectivesThe present study was undertaken in the Indraprastha Apollo Hospital to assess the transfusion requirement in cadaveric and living liver transplant patients so as to assess the maximum surgical blood ordering schedule (MSBOS) for each category.Materials & methods104 liver transplants performed from October 2006 to September 2008 were included in the study. The cases were divided into 2 subgroups: Cadaveric liver transplant (CLT, n=3) and living donor liver transplants (LDLT, n=101) They were further divided into those who received >7 units of packed red blood cells (PRC) (n=62) and those who received less than 7 units PRC (n=42). The patients were given balanced general anesthesia. The transfusion trigger were set to hemoglobin <8 gm/dL, Platelet count <50,000/cu mm and PT >20 seconds. The mean PRC, Fresh frozen Plasma (FFP), random donor Platelet concentrate (RDP), Single donor Platelets (SDP) on cell separator and cryoprecipitate were assessed for both CLT and LDLT.ResultsOut of the 101 LDLT, 83 (82.1%) patients were males and 18 (17.9%) were females whereas all the CLT were males. The mean PRC, FFP, RDP, SDP and cryoprecipitate utilization for LDLT were 8.84 units, 7.1 units, 1.83 units, 2.36 units and 2.03 units respectively whereas for CLT it was 15.3 units, 9 units, 0 units, 2.3 units & 3.3 units. The mortality rate in LDLT was 20 patients (19.8%) out of which 17 (85%) were males and 3 (15%) were females whereas in CLT the mortality rate was 1 patient (33.3%) who was a male (100%).
Journal: Apollo Medicine - Volume 5, Issue 4, December 2008, Pages 383-386