Diabetic ketoacidosis induced cerebral infarct: A missing link in pathogenesis of neurologic manifestations of acute pancreatitis

Diabetic ketoacidosis (DKA) is a known complication of acute pancreatitis (AP). On the other hand, ketosis can induce AP. Ketoacidosis along with AP induces an inflammatory cascade by oxidative stress and dehydration. Both of these factors lead to stasis of blood and endothelial damage which makes these patients prothrombotic. We report a case of DKA precipitated by AP. This patient developed watershed infarct in brain during her course of disease which was possibly attributed to hypercoagulability, stasis and endothelial injury triggered by ketosis.