Post Transplant Malignancy – A Brief Review

Immunosuppressed allograft recipients have three to five folds increase in cancer risk as compared to age matched general population. The most common malignancies encountered are Non Melanotic Skin Cancer, Post Transplant Lymphoproliferative Disorder and Kaposi's Sarcoma. Duration of immunosuppressive therapy and/or type of immunosuppressive agents are important controllable factors which have an impact in the development of tumors. Oncogenic viruses have an important role in the development of these malignancies.