کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3237531 1588861 2016 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Increased risk of chronic liver disease in patients with bipolar disorder: A population-based study
ترجمه فارسی عنوان
افزایش خطر ابتلا به بیماری مزمن کبدی در بیماران مبتلا به اختلال دوقطبی: یک مطالعه مبتنی بر جمعیت
کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی طب اورژانس
چکیده انگلیسی

ObjectiveThis study aimed to investigate the prevalence and incidence of chronic liver disease in patients with bipolar disorder.MethodsWe used a random sample of 766,427 subjects aged ≥18 years from the National Health Research Institute database in the year 2005. Subjects with at least one primary diagnosis of bipolar disorder in 2005 were identified. Patients with a primary or secondary diagnosis of chronic liver disease were also defined. We compared the prevalence and associated factors of chronic liver disease between patients with bipolar disorder and the general population in 2005. We also compared the incidence of chronic liver disease in patients with bipolar disorder and the general population from 2006 to 2010.ResultsThe prevalence of chronic liver disease in patients with bipolar disorder (13.9%) was 2.68 times higher than that of the general population (5.8%) in 2005. The average annual incidence of chronic liver disease in patients with bipolar disorder from 2006 to 2010 was also higher than that of the general population (2.95% vs. 1.73%; risk ratio: 1.71; 95% confidence interval: 1.46–2.01).ConclusionsPatients with bipolar disorder had a significantly higher prevalence and incidence of chronic liver disease than those in the general population, and younger patients with bipolar disorder have a much higher prevalence and incidence than those in the general population. Male sex, second-generation antipsychotic or antidepressant use, and hyperlipidemia were associated factors for chronic liver disease in patients with bipolar disorder.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: General Hospital Psychiatry - Volume 42, September–October 2016, Pages 54–59
نویسندگان
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