Iatrogenic hypermagnesemia following Epsom salt enema

Constipation is a common problem in the older population. Among other treatment modalities, Epsom salt enema has been used in emergency rooms. Since Epsom salts are 100% magnesium sulfate and excreted wholly through the kidneys, hypermagnesemia may result from their use, particularly in patients with impaired renal function. A case of fatal iatrogenic hypermagnesemia resulting from the administration of an Epsom salt enema is presented here. We suggest that magnesium-containing enemas should be avoided in patients with impaired renal function.