کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3247468 1589161 2012 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Recurrent Respiratory Depression Associated with Fentanyl Transdermal Patch Gel Reservoir Ingestion
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی طب اورژانس
پیش نمایش صفحه اول مقاله
Recurrent Respiratory Depression Associated with Fentanyl Transdermal Patch Gel Reservoir Ingestion
چکیده انگلیسی

BackgroundOpioid abuse is common in the United States and is currently on the rise. Fentanyl transdermal patches (FTPs) have been on the market since 1991, and have recently become a popular source of opioids for abusers. There are currently two distinct FTP designs available on the market today; a gel reservoir system and a matrix construct. The gel reservoirs of FTPs contain massive amounts of fentanyl and are easily extractable for abuse. Ingesting the gel reservoir of an FTP is potentially lethal.Case SeriesIn this case series, 4 patients ingested the gel reservoir of an FTP and experienced severe and recurrent respiratory depression necessitating continuous naloxone infusions. All patients responded adequately to initial prehospital doses of naloxone (0.8–2 mg intravenous) but developed recurrent respiratory depression within 2 h of presentation to the hospital.ConclusionThe gel reservoir of an FTP contains massive amounts of fentanyl. Ingestion of the gel may cause severe and recurrent respiratory depression necessitating repeated naloxone boluses, continuous naloxone infusion, and a prolonged observation period.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: The Journal of Emergency Medicine - Volume 42, Issue 5, May 2012, Pages 543–548
نویسندگان
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