کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3251706 | 1207009 | 2015 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
An unusual complex karyotype in myopericytoma
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موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
طب اورژانس
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: An unusual complex karyotype in myopericytoma An unusual complex karyotype in myopericytoma](/preview/png/3251706.png)
چکیده انگلیسی
IntroductionMyopericytoma is a perivascular neoplasm commonly found in the skin and soft tissue of extremities. These lesions often exhibit concentric vascular proliferation of spindle shaped myoid cells.Methods/ResultsWe present a case of a 76-year old male who was diagnosed with myopericytoma and subsequent cytogenetic analysis found a highly abnormal karyotype. This karyotype includes cytogenetic mutations that have not been described in previous case studies of myopericytoma.ConclusionsSome of these aberrations occur on genes that are involved in hedgehog signaling as well as pericyte proliferation, indicating a potential pericyte origin for myopericytoma tumors.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Orthopaedics - Volume 12, Issue 1, March 2015, Pages 58–62
Journal: Journal of Orthopaedics - Volume 12, Issue 1, March 2015, Pages 58–62
نویسندگان
Aaron W. James, Le Chang, Swati Shrestha, Carlos A. Tirado, Sarah M. Dry,