کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3261662 1207704 2015 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Helicobacter infections with rare bacteria or minimal gastritis: Expecting the unexpected
ترجمه فارسی عنوان
عفونت هلیکوباکتر باکتریهای نادر یا حداقل گاستریت: انتظار غیر منتظره
کلمات کلیدی
گاستریت، ایمونوهیستوشیمی، لکه های ویژه
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی غدد درون ریز، دیابت و متابولیسم
چکیده انگلیسی

BackgroundThe routine use of special stains for detection of Helicobacter remains controversial.AimsTo determine the frequency of histologically atypical Helicobacter infection.MethodsAll gastric biopsies received at a large pathology reference laboratory over a 6-month period were stained for Helicobacter, and the histologic and clinicopathologic parameters evaluated.ResultsAmongst 7663 Helicobacter-positive biopsies, 823 (10.7%) did not show typical chronic active gastritis with numerous Helicobacter organisms, and were therefore considered histologically atypical. Rare Helicobacter pylori organisms accounted for 58.0% of all atypical infections; the next most common atypical Helicobacter infection was that with minimal or no gastric inflammation (23.3% of atypical infections). Patients in these groups did not differ demographically from those with other forms of atypical or typical Helicobacter infection, although a small subgroup (6%) was more likely to have had a previously treated infection.ConclusionsIn many of these atypical infections, Helicobacter would not have been suspected based on the histologic findings alone, and would have been missed without routine special stains. Performing a sensitive stain could prevent additional testing and allow prompt treatment of the affected patients, thus substantially reducing the risk for peptic ulcer and gastric cancer and preventing the transmission of the infection to family members.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Digestive and Liver Disease - Volume 47, Issue 7, July 2015, Pages 549–555
نویسندگان
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