کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3262216 1207726 2014 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Chemotherapy versus self-expanding metal stent as primary treatment of severe dysphagia from unresectable oesophageal or gastro-oesophageal junction cancer
ترجمه فارسی عنوان
شیمیدرمانی در برابر استنت فلزی که خود را در حال گسترش است به عنوان درمان اولیه دیسفاژی شدید از سرطان اتصال ناخودآگاه غذا یا گوارشی در دستگاه گوارش
کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی غدد درون ریز، دیابت و متابولیسم
چکیده انگلیسی

ObjectiveTo compare chemotherapy first (group 1) versus self-expanding metal stent first (group 2) for the management of malignant dysphagia in unresectable oesophageal or gastro-oesophageal junction cancer.MethodsPatients from two university hospitals with severe malignant dysphagia (dysphagia score ≥ 2) uneligible for surgery or radiochemotherapy were evaluated retrospectively.ResultsForty-two patients were included in group 1, and 29 in group 2. After 4 weeks, dysphagia scores improved by at least 1 point in 67% of patients in group 1 versus 93% in group 2 (p = 0.01); 48% of patients in group 1 were able to eat solid food versus 68% in group 2 (p = 0.054). In group 1, a self-expanding metal stent was secondarily placed in 18 patients (42.9%), whereas in group 2 dysphagia required a second self-expanding metal stent placement in 33.3% of patients.ConclusionChemotherapy as the first treatment may be a valid option, avoiding self-expanding metal stent insertion in half of the patients.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Digestive and Liver Disease - Volume 46, Issue 3, March 2014, Pages 283–286
نویسندگان
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