کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3262853 1207745 2012 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Bowel preparation with polyethylene glycol electrolyte solution: Optimizing the splitting regimen
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی غدد درون ریز، دیابت و متابولیسم
پیش نمایش صفحه اول مقاله
Bowel preparation with polyethylene glycol electrolyte solution: Optimizing the splitting regimen
چکیده انگلیسی

AimQuality of bowel cleansing significantly increases the shorter the time between bowel solution intake and endoscopic examination. We tested the efficacy and patient tolerability following a modified polyethylene glycol electrolyte (PEG) splitting regimen.MethodsThis was a prospective, single-blind, randomized, study. Patients were assigned to receive either PEG 4 L the afternoon before colonoscopy or PEG 3 L the day before and 1 L 3 h before the procedure the day of colonoscopy.ResultsThe study population consisted of 336 patients, including 168 participants in each study arm. Although the bowel preparation quality was similarly quoted as excellent/good following the split and full regimen (95.2% vs 92.8%; p = 0.3), a significant (p < 0.0001) shift from good towards an excellent preparation (26.8% vs 68.4%) was observed following the split regimen as compared to the full regimen (55.4% vs 37.5%). The incidence of side-effects did not differ. When patients were asked about a future preparation if needed, 69% and 31% following the split and full regimen, respectively, declared to accept again the same preparation, the difference being statistically significant (p < 0.001).ConclusionsOur data found that an excellent bowel cleansing could be frequently achieved by simply modifying the split regimen from the standard PEG 2 plus 2 L to 3 plus 1 L.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Digestive and Liver Disease - Volume 44, Issue 7, July 2012, Pages 576–579
نویسندگان
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