کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3266779 1207870 2006 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Eosinophilic gastroenteritis with severe protein-losing enteropathy: Successful treatment with budesonide
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی غدد درون ریز، دیابت و متابولیسم
پیش نمایش صفحه اول مقاله
Eosinophilic gastroenteritis with severe protein-losing enteropathy: Successful treatment with budesonide
چکیده انگلیسی

We report the clinical, laboratory, endoscopic and histopathological findings in a 40-year-old woman with watery diarrhoea and hypoproteinaemia. Elevated α1-antitrypsin clearance confirmed massive protein-losing enteropathy. Gastroscopic and colonoscopic biopsies showed abundant infiltration of the small bowel wall with eosinophils in proximal duodenum and terminal ileum, respectively. These findings established the diagnosis of eosinophilic gastroenteritis. Both the inflammatory alterations and the severe intestinal protein loss were successfully treated with budesonide, a topically active corticosteroid preparation with controlled small bowel release. The case report illustrates that remission of protein-losing enteropathy secondary to eosinophilic gastroenteritis can be achieved with budesonide, thus supporting its use for this uncommon disease characterised by inflammatory intestinal lesions.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Digestive and Liver Disease - Volume 38, Issue 1, January 2006, Pages 55–59
نویسندگان
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