Facteurs nutritionnels et troubles cognitifs chez le sujet âgé

Environmental factors that increase or decrease the incidence of Alzheimer's disease (AD) have not been well identified. Large epidemiological studies have explored the associations between diet/nutrients and dementia/AD or cognitive decline. Studies suggest that intake of fish, vitamins C and E, unsaturated fatty acids or a moderate amount of wine are related to a low incidence of dementia or AD. Few studies suggest that high midlife serum cholesterol is related to a high incidence of dementia or AD. However, these observational data don't demonstrate a causal relationship between the intake of a nutrient and the incidence of dementia. We need further clinical trials to show that a nutrient can be a risk factor or a protective factor for dementia or AD.