کد مقاله کد نشریه سال انتشار مقاله انگلیسی ترجمه فارسی نسخه تمام متن
328084 543070 2016 6 صفحه PDF سفارش دهید دانلود رایگان
عنوان انگلیسی مقاله ISI
Predictors of Continued Use of Extended-Released Naltrexone (XR-NTX) for Opioid-Dependence: An Analysis of Heroin and Non-Heroin Opioid Users in Los Angeles County
ترجمه فارسی عنوان
پیش بینی استفاده مداوم از نالترکسون گسترده (XR-NTX) برای وابستگی به مواد مخدر: تجزیه و تحلیل استفاده کنندگان از مواد مخدر هروئین و غیر هروئین در شهر لس آنجلس
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کلمات کلیدی
اختلال مصرف مواد افیونی؛ نالترکسون با رهش طولانی ؛ هروئین؛ اپیوئیدها؛ درمان به کمک دارو
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی روانپزشکی بیولوژیکی
چکیده انگلیسی


• Some studies suggest better pharmacotherapy adherence and/or retention rates among non-heroin opioid users compared to heroin users. Therefore, this study examined predictive associations of subsequent doses of extended-release naltrexone (XR-NTX) among heroin and non-heroin opioid users.
• Non-heroin opioid users and heroin users are retained in XR-NTX treatment for comparable periods of time. However, those who identify as homeless, inject opioids (regardless of opioid-type), or were diagnosed with a mental illness are less likely to be retained in treatment with XR-NTX.
• Further, XR-NTX may contribute to decreases in urges to use among heroin and non-heroin opioid users.

Extended-release naltrexone (XR-NTX) is associated with an increased number of opioid-free days, improved adherence rates in substance use disorder treatment programs, and reduced cravings and drug-seeking behaviors. There is little evidence on the predictive associations between baseline characteristics of opioid-dependent patients and XR-NTX utilization. Some studies have demonstrated better pharmacotherapy adherence and/or retention rates among non-heroin opioid users compared to heroin users. This study examines predictive associations between characteristics of patients and XR-NTX utilization, as well as participants’ urge to use opiates. Our findings suggest that XR-NTX may contribute to decreases in urges to use among both heroin and non-heroin opioid users. Non-heroin opioid users and heroin users were retained in XR-NTX treatment for comparable periods of time. However, those who identified as homeless, injected opioids (regardless of opioid-type), or were diagnosed with a mental illness were less likely to be retained in treatment with XR-NTX.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Substance Abuse Treatment - Volume 63, April 2016, Pages 66–71
نویسندگان
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