Pathology of NASH and fibrosis

Non-alcoholic steatohepatitis (NASH) is a progressive liver disease that has gained recognition in the last two decades. It may even account for some of the cases previously diagnosed as cryptogenic cirrhosis. Association of this entity with obesity, insulin resistance and type-II diabetes is well documented. In this review, patterns of liver fibrosis in NASH, its pathogenesis and staging systems are discussed.