کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
328144 543086 2007 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Elevated prolactin serum levels and history of alcohol withdrawal seizures
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی روانپزشکی بیولوژیکی
پیش نمایش صفحه اول مقاله
Elevated prolactin serum levels and history of alcohol withdrawal seizures
چکیده انگلیسی

BackgroundProlactin has been discussed to be useful for differential diagnosis in epilepsia. Aim of the present study was to investigate the association between prolactin serum levels and previous alcohol withdrawal seizures.MethodsWe assessed 118 male patients admitted for detoxification treatment. Previous withdrawal seizures were recorded and prolactin serum levels were measured using an enzymatic immunoassay.ResultsPatients with a history of alcohol withdrawal seizures had significantly higher prolactin levels (17.8 ng/ml, SD = 12.1) than patients without previous seizures (13.0 ng/ml, SD = 8.1, p < 0.05). Logistic regression revealed significant predictive qualities for prolactin serum levels (B = 0.05, Wald = 5.30, p = 0.021, OR = 1.06, 95%CI = 1.01–1.11).ConclusionsThe present findings show an association between elevated prolactin serum levels and a history of withdrawal seizures. Hence, the results suggest that prolactin elevation at admission may be a clinical marker for an increased risk of withdrawal seizures.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Psychiatric Research - Volume 41, Issue 8, October 2007, Pages 702–706
نویسندگان
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