Colchicine or Methotrexate, With Ursodiol, Are Effective After 20 Years in a Subset of Patients With Primary Biliary Cirrhosis

Treatment with the combination of UDCA and MTX or UDCA and colchicine led to sustained clinical remission in a subset of patients with PBC. The response to the combination of UDCA and MTX appeared to be more durable than to UDCA and colchicine.