کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3286293 1209291 2011 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Interplay between p53-family, their regulators, and PARPs in DNA repair
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی بیماری‌های گوارشی
پیش نمایش صفحه اول مقاله
Interplay between p53-family, their regulators, and PARPs in DNA repair
چکیده انگلیسی

SummaryAbnormalities of the p53 tumor suppressor gene are among the most frequent molecular events in human neoplasia. p53 is consequently one of the most studied proteins, and is the subject of over 55,500 scientific papers. In this review, attention is focused on the functions of p53 in DNA repair. We highlight the recent progress in the analysis of protein signals to p53, including PARPs, and ubiquitination cascade proteins MDM2, CRM1, USP10 and 14-3-3σ.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Clinics and Research in Hepatology and Gastroenterology - Volume 35, Issue 2, February 2011, Pages 98–104
نویسندگان
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