A low-residue diet improved patient satisfaction with split-dose oral sulfate solution without impairing colonic preparation

BackgroundPreprocedural dietary restrictions have been identified as a common reason potential candidates for colorectal cancer screening do not undergo colonoscopy as recommended.ObjectiveTo study whether a low-residue diet impacts bowel preparation with oral sulfate solution.DesignEndoscopist blinded, prospective, randomized controlled trial.SettingCommunity-based outpatient ambulatory surgical center.PatientsPatients scheduled for outpatient colonoscopy.InterventionsSubjects were randomized to ingest either a low-residue diet of specified foods for breakfast, lunch, and snack or a clear liquid diet the day before the colonoscopy.Main Outcome MeasurementsThe quality of the bowel preparation was assessed using the Boston Bowel Preparation Scale. Subject satisfaction with bowel preparation, diet, and severity of side effects was measured by a visual analog scale.ResultsTwo hundred thirty subjects were recruited (114 clear liquid and 116 low residue). Mean preparation scores were not statistically different in either their segmental scores or total score. Subjects in the low-residue arm reported significantly higher satisfaction with bowel preparation medication, diet, and entire preparation process. Observed rates of side effects were low, and there was no statistical difference between the two groups. The rate of procedural cancellation was significantly higher in the clear liquid group compared with the low-residue group (20% vs 9%, P = .03).LimitationsSingle-center study.ConclusionsA low-residue diet did not impair the quality of bowel preparation achieved with split-dose oral sulfate solution but did improve patient satisfaction.