کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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3303782 | 1210322 | 2014 | 10 صفحه PDF | دانلود رایگان |
BackgroundMalignant gastric outlet obstruction is often treated by stent placement.ObjectiveTo investigate the outcomes of stent placement in the palliative treatment of malignant neoplasms.DesignProspective, observational, multicenter registry.SettingSix tertiary care centers in 5 countries.PatientsA total of 108 adult patients with malignant gastric outlet obstruction.InterventionsPlacement of an uncovered, self-expandable, metal duodenal stent.Main Outcome MeasurementsThe primary endpoint was stent patency at 14 days after stent implantation. Secondary endpoints included stent patency at 1, 2, 3, and 6 months, gastric outlet obstruction scoring system (GOOSS) scores at 14 days and 1, 2, 3, and 6 months after stent deployment, technical success, adverse events, and patient survival (ie, confirmed duration of the implant).ResultsTechnical success was achieved in 99.1% of stent placements. Stent patency at 14 days was 94.6%. Kaplan-Meier estimates of stent patency were 92.9% at 1 month, 86.2% at 2 months, 81.9% at 3 months, and 63.4% at 6 months. At 14 days, GOOSS scores increased by a median of 1 point. The overall GI adverse event rate was 32.4%; however, the stent-related adverse event rate was 19.4%. The median implant duration was 47 days (range 0-195 days).LimitationsObservational study, no control group.ConclusionsDuodenal stent placement resulted in prompt relief of malignant gastric outlet obstruction and improved GOOSS scores. (Clinical trial registration number: NCT00991614.)
Journal: Gastrointestinal Endoscopy - Volume 79, Issue 1, January 2014, Pages 66–75