کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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3305183 | 1210350 | 2009 | 5 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Reflux of duodenal contents and cholangitis in patients undergoing self-expanding metal stent placement Reflux of duodenal contents and cholangitis in patients undergoing self-expanding metal stent placement](/preview/png/3305183.png)
BackgroundIt has been reported that the occurrence of acute cholangitis is common, especially when the self-expanding metal stent (SEMS) is placed across the main duodenal papilla.ObjectiveTo determine the incidence of duodenobiliary reflux and acute cholangitis after placement of SEMSs across the main duodenal papilla.DesignA prospective study.SettingA tertiary-care teaching hospital.PatientsOne hundred consecutive patients with malignant bile-duct obstruction.InterventionsA barium meal examination was performed 21 days after placement of SEMSs. Reflux of barium was monitored by using fluoroscopy. The patients were also monitored for the occurrence of fever. Serum bilirubin, alanine aminotransferase, alkaline phosphatase, and total and differential leukocyte counts were evaluated before and after the barium study.Main Outcome MeasurementsThe occurrence of duodenobiliary reflux and acute cholangitis.ResultsTwo patients developed acute cholangitis because of the failure of the function of the SEMS, and they died during the first week. Severe reflux of barium was evident in all the patients. However, none of them developed features of acute cholangitis because of reflux. After a mean (SD) follow-up of 6.4 ± 1 months, 6 patients developed acute cholangitis because of blockage of the SEMS from ingrowth of tumor or collection of debris at the lower end of the SEMS.LimitationsUnblinded study.ConclusionsAfter placement of SEMSs across the main duodenal papilla, reflux of duodenal contents is a universal phenomenon. Acute cholangitis was observed only in cases with blockage of the SEMS from tumor ingrowth or debris.
Journal: Gastrointestinal Endoscopy - Volume 70, Issue 2, August 2009, Pages 317–321