کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3306262 1210366 2009 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
A hinged metalloplastic anastomotic device: a novel method for choledochoduodenostomy
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی بیماری‌های گوارشی
پیش نمایش صفحه اول مقاله
A hinged metalloplastic anastomotic device: a novel method for choledochoduodenostomy
چکیده انگلیسی

BackgroundIn biliary obstruction, the creation of a large-diameter permanent fistula between the bile duct and the duodenum would be attractive.ObjectiveTo invent, prototype, and test a new method of forming a biliary duodenal anastomosis.DesignSurvival and nonsurvival porcine model.SettingAn animal laboratory with general anesthesia.InterventionA novel hybrid metalloplastic 7F anastomosis device that consisted of a central ferrous metallic tube sandwiched between 2 tapered flexible plastic end pieces was used. The device was hinged on either side of the metal insert so that a magnetic force could form an anastomosis and then the plastic components of the device could deform to fall through the compression anastomosis. These devices were inserted into the bile duct of the pigs over a 0.035-inch guidewire with a pusher tube. Cylindrical-shaped magnets were then positioned over the intraduodenal bile duct so that they exerted compressive ischemic force on the duodenum and bile duct above the papilla.Main Outcome MeasurementsCholedochoduodenal anastomoses created were inspected at subsequent endoscopy and postmortem for patency and size.ResultsSeven anastomosis devices were placed in the bile duct of pigs (weight 22-54 kg). All 4 survival animals were well and eating as soon as they were awake. Anastomoses were successfully accomplished in all survival animals. The supra-ampullary opening into the bile duct ranged from 5 to 10 mm.LimitationThe small number of animals.ConclusionsA new method for achieving larger-diameter biliary drainage was developed. Four animals were euthanized after 2 to 7 days. Our best anastomosis resulted from 2 magnets left in the animals for 4 days.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Gastrointestinal Endoscopy - Volume 69, Issue 7, June 2009, Pages 1333–1338
نویسندگان
, , , ,