کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3307003 1210378 2010 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Appropriate indications for endoscopic submucosal dissection of early gastric cancer according to tumor size and histologic type
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی بیماری‌های گوارشی
پیش نمایش صفحه اول مقاله
Appropriate indications for endoscopic submucosal dissection of early gastric cancer according to tumor size and histologic type
چکیده انگلیسی

BackgroundEndoscopic submucosal dissection (ESD) is increasingly being performed for early gastric cancers (EGCs) that are larger than 2 cm and those that are not intestinal-type (IT) cancers by Lauren's classification. The technical feasibility of ESD for these EGCs has not been fully evaluated.ObjectiveTo identify appropriate expanded indications for ESD of EGC.Design and SettingA retrospective analysis of prospectively collected data was performed on consecutive patients who underwent ESD at a single tertiary center.Patients and MethodsIn total, 487 EGCs in 461 patients treated by ESD were classified by size and histologic type: IT EGCs 2 cm or less (257 lesions in 235 patients), IT EGCs larger than 2 cm (172 lesions in 168 patients), and non-IT EGCs (58 lesions in 58 patients).Main Outcome MeasurementsCurative resections were assessed among the 3 groups, and logistic regression analysis was used to analyze factors related to curative resection.ResultsThe rates of curative resection significantly decreased from IT EGCs 2 cm or less (88.7%) to IT EGCs larger than 2 cm (73.3%) to non-IT EGCs (37.9%). Tumor size (>3 cm), ulceration, histologic type (non-IT), and piecemeal resection were independently unfavorable factors in curative resection.LimitationsSmall sample size and short-term duration of follow-up study.ConclusionsESD with curative intent is technically most feasible for nonulcerative and IT EGCs smaller than 3 cm.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Gastrointestinal Endoscopy - Volume 71, Issue 6, May 2010, Pages 920–926
نویسندگان
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