کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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3308962 | 1210414 | 2008 | 8 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: WallFlex colonic stent placement for management of malignant colonic obstruction: a prospective study at two centers WallFlex colonic stent placement for management of malignant colonic obstruction: a prospective study at two centers](/preview/png/3308962.png)
BackgroundSelf-expanding metal stents (SEMSs) can alleviate malignant colonic obstruction and avoid emergency decompressive surgery. The use of colonic larger-diameter SEMSs may improve bowel function and reduce migration risk.ObjectiveTo evaluate the effectiveness and safety of a novel large-diameter SEMS (WallFlex) designed for delivery through the endoscope in treating malignant colonic obstruction.DesignProspective clinical cohort study.SettingTwo Italian study centers.PatientsForty-two consecutive patients with malignant colonic obstruction: 23 requiring palliation and 19 bridging to surgery.InterventionsColorectal SEMS placement.Main Outcome MeasurementsTechnical success, defined as accurate SEMS deployment across the stricture on the first attempt; clinical success, ie, complete relief of bowel obstruction without complications; and bridging to surgery, denoting the performance of elective one-stage surgery.ResultsThe rate of technical success was 93% (95% CI, 81%-99%) and of initial clinical success was 95% (95% CI, 84%-99%). In 58% (95% CI, 40%-84%) of the palliation group, clinical success was maintained after 6 months. All 19 patients with operable tumors were successfully bridged to one-stage elective surgery within a median of 5 days. One perforation and one stent migration occurred. All complications could be resolved nonsurgically.LimitationsNo control group was included.ConclusionsIn a prospective study of through-the-scope WallFlex stent placement for malignant colonic obstruction, high rates of technical and initial clinical success, and bridging to surgery were achieved. Complications could be readily managed.
Journal: Gastrointestinal Endoscopy - Volume 67, Issue 1, January 2008, Pages 77–84