کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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3309032 | 1210417 | 2007 | 5 صفحه PDF | دانلود رایگان |

BackgroundAlthough endoscopic stent placement is now generally accepted as a palliative treatment for gastric outlet obstruction resulting from gastric cancer, it carries potential limitations such as tumor ingrowth or migration.ObjectiveOur purpose was to evaluate the technical and clinical efficacy of endoscopic placement of a newly designed double-layered combination pyloric stent.DesignProspective, uncontrolled, single-center.SettingTertiary referral university hospital.PatientsEleven patients with gastric outlet obstruction by unresectable stomach cancer.InterventionsEleven patients received a double-layered combination pyloric stent (an outer uncovered stent to reduce migration and an inner polytetrafluoroethylene-covered stent to prevent tumor ingrowth).Main Outcome MeasurementTo evaluate technical success, clinical success, and complications, especially tumor ingrowth and migration.ResultsTechnical success was achieved in 11 of 11 (100%) patients. Among 11 patients in whom endoscopic stenting was placed successfully, clinical success was 90.9%, tumor ingrowth 0%, migration 9.1%, and tumor overgrowth 9.1%. Median stent patency period was 121 days.LimitationsSmall number of patients, uncontrolled study, short-term follow-up period.ConclusionsWe have described a technique for endoscopic metal stent placement by using the newly designed double-layered combination stent for gastric outlet obstruction by stomach cancer. This stent seems to be effective and looks promising for technical efficacy, clinical outcome, and preventing tumor ingrowth and migration.
Journal: Gastrointestinal Endoscopy - Volume 66, Issue 6, December 2007, Pages 1206–1210