Epidermoid cancers of the anal canal

Squamous cell cancer of the anal canal continues to be a rare cancer. Recently, the incidence has been slowly rising in part due to longer-term HIV survivors and in part due to high prevalence of HPV. Early detection and treatment in these high-risk groups is imperative to increasing the survival of the disease. Chemoradiation remains the standard of care for primary therapy, reserving surgical resection for salvage.