کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3319259 | 1211674 | 2015 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Premalignant neoplasms of the anus and perianal skin
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موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
بیماریهای گوارشی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Premalignant neoplasms of the anus and perianal skin Premalignant neoplasms of the anus and perianal skin](/preview/png/3319259.png)
چکیده انگلیسی
Squamous cell carcinoma of the anal canal is preceded by a spectrum of premalignant lesions known as anal intraepithelial neoplasia (AIN). AIN is caused by infection with the human papilloma virus (HPV), and the pathogenesis mimics that of cervical cancer. It is most commonly associated with HIV infection and high-risk sexual behavior. Symptoms of AIN may mimic benign processes. Multiple screening approaches exist for detecting HPV and dysplasia, but so far there is no standard algorithm. Several treatment options for AIN exist, although recurrence remains high. Regular surveillance by a surgeon is key after successful treatment. Extramammary perianal Paget׳s disease (EMPD) is another premalignant lesion. It is an intraepithelial adenocarcinoma that may or may not be associated with underlying malignancy. There are limited cases reported in the literature, and a staging method has been proposed. Both AIN and EMPD will be discussed in the following chapter.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Seminars in Colon and Rectal Surgery - Volume 26, Issue 2, June 2015, Pages 96-102
Journal: Seminars in Colon and Rectal Surgery - Volume 26, Issue 2, June 2015, Pages 96-102
نویسندگان
Andrew MD, Juan Lucas MD, MS, FACS, FASCRS,