کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3319281 | 1211676 | 2014 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Patient selection for neoadjuvant therapy of rectal adenocarcinoma
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موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
بیماریهای گوارشی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Patient selection for neoadjuvant therapy of rectal adenocarcinoma Patient selection for neoadjuvant therapy of rectal adenocarcinoma](/preview/png/3319281.png)
چکیده انگلیسی
Rectal adenocarcinomas are typically treated with a combination of radiotherapy, chemotherapy, and surgical resection. Risk factors for local recurrence include tumor stage, nodal stage, tumor location, circumferential resection margin status, and surgical technique. Most patients receive pre-operative therapy based on staging evaluations using endorectal ultrasound and/or pelvic MRI. Pre-operative therapy is recommended for any patient with T3-4 disease or nodal involvement. Subgroups of patients defined by combinations of stage and tumor location are at very low risk for local recurrence after surgery alone and may benefit from initial surgery followed by selective post-operative therapy based on pathologic results. Prospective studies are needed to validate therapy de-intensification approaches.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Seminars in Colon and Rectal Surgery - Volume 25, Issue 1, March 2014, Pages 2-5
Journal: Seminars in Colon and Rectal Surgery - Volume 25, Issue 1, March 2014, Pages 2-5
نویسندگان
Stephen L. MD,