HLA Antibody Incompatible Transplantation – A mini review

Antibody incompatible transplantation (AiT) is on the rise. This is because of advances in detection of donor specific antibodies, even at very low levels. In spite of this there is an increased risk of acute antibody mediated rejection. There are multiple protocols to prevent and treat antibody mediated rejection. Though they are reasonably successful in reversing acute rejection, graft loss still occurs due to ongoing chronic antibody mediated rejection.