کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3354931 1591449 2009 12 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Depression and Immunity: Inflammation and Depressive Symptoms in Multiple Sclerosis
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی ایمونولوژی، آلرژی و روماتولوژی
پیش نمایش صفحه اول مقاله
Depression and Immunity: Inflammation and Depressive Symptoms in Multiple Sclerosis
چکیده انگلیسی

An increasing body of evidence suggests that patients who have major depressive disorder show alterations in immunologic markers including increases in proinflammatory cytokine activity and inflammation. Inflammation of the central nervous system is a pathologic hallmark of multiple sclerosis (MS). Patients affected by this disease also show a high incidence of depression. Accumulating evidence from animal studies suggests that some aspects of depression and fatigue in MS may be linked to inflammatory markers. This article reviews the current knowledge in the field and illustrates how the sickness behavior model may be applied to investigate depressive symptoms in inflammatory neurologic diseases.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Immunology and Allergy Clinics of North America - Volume 29, Issue 2, May 2009, Pages 309–320
نویسندگان
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