کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3383389 | 1220455 | 2011 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Seguridad de las terapias biológicas: nuevos datos de BIOBADASER
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موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
ایمونولوژی، آلرژی و روماتولوژی
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چکیده انگلیسی
The study of the long-term safety of biological therapies has been made possible because of the creation of several national registries. These have resolved some of the safety-derived doubts from the initial clinical trials, observational studies and meta-analyses. The main problem associated with biological therapy use is a moderate increase in the risk of serious infections when compared to conventional therapies. However, this risk can be reduced with adequate preventative measures. It seems that there is neither an increased risk of cancer nor elevated mortality with the use of biological drugs. These adverse events, along with others such as paradoxical induction of psoriasis, demyelinating diseases and administration-related reactions, have been studied in BIOBADASER, the Spanish Registry of Biological Therapies. This paper reviews the safety of biological agents with a special focus on BIOBADASER studies
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: ReumatologÃa ClÃnica - Volume 6, Supplement 3, March 2011, Pages 1-6
Journal: ReumatologÃa ClÃnica - Volume 6, Supplement 3, March 2011, Pages 1-6
نویسندگان
Carlos RodrÃguez Lozano,