Les hypersensibilités digestives aux aliments non IgE médiées

Food hypersensitivities with a digestive tropism can have an allergenic or non-allergenic origin. The forms with an allergic mechanism have either an IgE-based immediate mechanism or a more complex non-IgE-based mechanism, notably a cell-based response. Other types of hypersensitivities can be mixed, for example, an IgE response based on a delayed hypersensitivity background. The IgE-dependant forms are the best known because they are the easiest to diagnose using a conventional allergy workup, but it is equally necessary to know the clinical expression of non-IgE mediated forms because they are frequent and if due to the same allergens, the usual allergy workup is not valuable; their diagnosis is based on the patient's history and on the result of provocation tests.