Profil clinique des réactions aux corticoïdes

Corticoids have been used in a topical form for their anti-inflammatory, immunosuppressive and anti-proliferative properties more than 60 years. Compared to their classic secondary effects such as cutaneous atrophy, stretch marks, teliangiectases and pigmentary problems, described especially after prolonged use of strong dermato-corticoids, delayed allergic hypersensitivity reactions have been described only more recently. These reactions were overlooked for a long time because of the therapeutic anti-inflammatory effect of these molecules. Sensitization occurs by far most frequently through the skin while contact eczemas may also arise following inhalation or installation of eye drops containing corticoids.