کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3391082 | 1220997 | 2010 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
SÃndrome de sinovitis, acné, pustulosis, hiperostosis, osteÃtis y tratamiento con antagonistas del factor de necrosis tumoral
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
ایمونولوژی، آلرژی و روماتولوژی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
SAPHO syndrome (synovitis, acne, pustulosis, hyperostosis, osteitis) encompasses a group of osteoarticular manifestations, especially hyperostosis in the joints and bones of the anterior chest wall and skin in the form of severe acne or hidradenitis. In the treatment of this syndrome, whose pathogenesis is unknown, many drugs have been used such as nonsteroidal anti-inflammatory agents and antibiotics. Corticosteroids, methotrexate, sulfasalazine and intravenous bisphosphonates have been used mainly in refractory cases. The development of biological treatments, indicated in certain rheumatic diseases, has provided a new therapeutic option, especially in patients without response. Anti-tumor necrosis factor-alfa agents, specifically infliximab and etanercept, have been used in isolated cases and small series. In general, the results have been satisfactory and these drugs can be an effective alternative to conventional treatments.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Seminarios de la Fundación Española de ReumatologÃa - Volume 11, Issue 1, JanuaryâMarch 2010, Pages 2-6
Journal: Seminarios de la Fundación Española de ReumatologÃa - Volume 11, Issue 1, JanuaryâMarch 2010, Pages 2-6
نویسندگان
Daniel Pielfort Garrido, Ángel M. GarcÃa Aparicio,