کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3405977 1223493 2015 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Restrictive reporting of selected antimicrobial susceptibilities influences clinical prescribing
ترجمه فارسی عنوان
گزارش محدودی از حساسیت های ضد میکروبی انتخاب شده بر روی تجویز بالینی تاثیر می گذارد
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی بیماری های عفونی
چکیده انگلیسی

SummaryBackgroundCascade and restrictive reporting are useful strategies to enhance antibiotic stewardship programs.MethodsWe combined both strategies to improve the prescribing of antibiotics aimed at Gram-negative infections.ResultsFor Enterobacter aerogenes, the susceptibility rates to amikacin increased from 10% to 100%; for third generation cephalosporins, these rates increased from 55% to 89%. The susceptibility rates of E. aerogenes to cefepime and piperacillin–tazobactam changed little, and the ampicillin susceptibility decreased from 30% in 2009 to 11% in 2010. For Proteus mirabilis, the susceptibility rates increased for third-generation cephalosporins (48% vs. 92%) and piperacillin–tazobactam (10% vs. 98%), with minimal changes for cefepime (96% vs. 93%), ampicillin (69% vs. 73%) and amikacin (96% vs. 84%). For Pseudomonas aeruginosa, the susceptibility rates improved slightly for third-generation cephalosporins (81% vs. 91%) but reduced for piperacillin–tazobactam (99% vs. 59%). Hospital-acquired Clostridium difficile infections decreased from 0.11 to 0.07 per 1000 patient days.ConclusionsSelective reporting helps physicians choose the most appropriate antibiotics for their patients within a stewardship program, with reduced C. difficile infection.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Infection and Public Health - Volume 8, Issue 3, May–June 2015, Pages 234–241
نویسندگان
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