کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3406021 1223495 2015 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Hemophagocytic lymphohistiocytosis with a leukemoid reaction in an infant with scrub typhus
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی بیماری های عفونی
پیش نمایش صفحه اول مقاله
Hemophagocytic lymphohistiocytosis with a leukemoid reaction in an infant with scrub typhus
چکیده انگلیسی

SummaryA two-month-old male infant presented with a clinical picture suggestive of fever without focus. Treatment was initiated with broad spectrum intravenous antibiotics. The infant subsequently developed septic shock, hepatosplenomegaly and tachypnoea with oxygen dependency. There was laboratory evidence of anemia, thrombocytopenia and a leukemoid reaction. Infection induced hemophagocytic lymphohistiocytosis with a leukemoid reaction was suspected because of fever, splenomegaly and bicytopenia in conjunction with elevated serum triglycerides and ferritin. Empiric therapy with doxycycline caused a rapid resolution of the fever, and the diagnosis of scrub typhus was confirmed by a positive scrub IgM ELISA. HLH with a leukemoid reaction secondary to scrub typhus has not previously been reported in early infancy.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Infection and Public Health - Volume 8, Issue 6, November–December 2015, Pages 626–629
نویسندگان
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