کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3406174 1223507 2013 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Determining the severity of Plasmodium falciparum malaria in Ethiopia
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی بیماری های عفونی
پیش نمایش صفحه اول مقاله
Determining the severity of Plasmodium falciparum malaria in Ethiopia
چکیده انگلیسی

SummaryBackgroundIn the majority of health centers in Ethiopia, the severity of falciparum malaria has been determined by parasitemia alone. However, it has been suggested that the use of peripheral infected RBC counts as an indicator of disease severity by itself is insufficient. Therefore, this study was performed to assess the severity of falciparum malaria infection in three Ethiopian localities with epidemic malaria and to compare the usual severe malaria determination technique (parasitemia) used in Ethiopia with other malaria severity determination parameters: circulatory collapse, cerebral malaria and severe anemia.MethodsBlood samples were collected from 400 individuals to examine the presence of falciparum malaria in the Awash, Metehara and Ziway areas of Ethiopia. Data on cerebral malaria, circulatory collapse and severe anemia were collected from 210 falciparum malaria patients.ResultsOf the 400 individuals examined, 210 were positive for falciparum malaria, and 190 were negative and served as healthy controls (HC). Severe anemia (18 patients, 8.57%) and circulatory collapse (25 patients, 11.90%) were the common features associated with severe falciparum malaria. Additionally, the detection of severe malaria was comparable using parasitemia, circulatory collapse or anemia.ConclusionThe findings of this study demonstrated comparable capacity for detecting severe falciparum malaria using circulatory collapse, severe anemia or parasitemia. Therefore, in addition to parasitemia, assessing severity of falciparum malaria using circulatory collapse and severe anemia will facilitate the diagnosis and management of malaria in Ethiopia.


► Severe anemia (18 patients, 8.57%) andcirculatory collapse (25 patients, 11.90%) were the common features associatedwith severe falciparum malaria. Parasitemia and cerebral malariaoccurred in 17 (8.09%) and 6 (2.86%) of the patients, respectively.
► The detection of severe malaria wascomparable using parasitemia, circulatory collapse or anemia.
► In addition to parasitemia, assessingseverity of falciparum malaria using circulatory collapse and severeanemia will facilitate the diagnosis and management of malaria in Ethiopia.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Infection and Public Health - Volume 6, Issue 1, February 2013, Pages 10–15
نویسندگان
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