Topical 5-fluorouracil for treatment of cervical intraepithelial neoplasia 2: a randomized controlled trial

Topical 5-FU appears to be an effective medical therapy for CIN 2 in young women. 5-FU is readily available and may be considered as an off-label treatment option for young women with CIN 2 who are interested in the treatment of disease but want to avoid excisional procedures.