کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3433632 1594921 2014 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The “anathema” of arbitrary categorization of continuous predictors
کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی پزشکی و دندانپزشکی (عمومی)
پیش نمایش صفحه اول مقاله
The “anathema” of arbitrary categorization of continuous predictors
چکیده انگلیسی

In medicine in general, and in obstetrics in particular, it is common practice to use arbitrary cutoffs in expressing continuous variables. However, the dichotomy of continuous data is associated with loss of statistical power, which may result in inaccurate estimates in clinical prognosis or prediction of outcomes and, consequently, may lead to incorrect inferences. If the predictor is a continuous variable, arbitrary percentile-based categorizations without clinical justification is an anathema (Greek word meaning “curse”) and should be discouraged. Instead, the clinical outcome of interest should be defined first and then a receiver operating characteristic curve analysis or other appropriate statistical techniques should be employed to determine the most optimal cutoff of the predictor. The next step should be to validate the cutoff in a different population before introducing it to clinical use or interventional trials.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: American Journal of Obstetrics and Gynecology - Volume 210, Issue 3, March 2014, Pages 200–203
نویسندگان
, , ,