Neuroprotective peptides prevent some alcohol-induced alteration in γ-aminobutyric acid A-β3, which plays a role in cleft lip and palate and learning in fetal alcohol syndrome

Treatment with the neuropeptides NAPVSIPQ and SALLRSIPA prevented the alcohol-induced decline in GABAβ3 expression 10 days after alcohol exposure. Because palate formation continues through E18, NAPVSIPQ and SALLRSIPA may be beneficial for the prevention of cleft lip and palate.